Crystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine Kinase
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چکیده
منابع مشابه
Crystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine Kinase
Human RON (Recepteur d'Origine Nantais) receptor tyrosine kinase is a cell surface receptor for Macrophage Stimulating Protein (MSP). RON mediates signal transduction pathways that regulate cell adhesion, invasion, motility and apoptosis processes. Elevated levels of RON and its alternatively spliced variants are implicated in the progression and metastasis of tumor cells. The binding of MSP α/...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0041912